In the year 2045, the world is recovering from a pandemic that left only a few men alive. Akane Ryuzoji, a tall and muscular nurse, is assigned to care for Reito Mizuhara, one of the few surviving men tasked with repopulating the earth. As Reito navigates this new reality, Akane is by his side, assertively ensuring his well-being and often indulging in her provocative tendencies.